Feb 29, 2016
This podcast highlights original research published in the March 2016 issue of Otolaryngology–Head and Neck Surgery, the official journal of the American Academy of Otolaryngology—Head and Neck Surgery (AAO-HNS) Foundation.
The indications for neck dissection concurrent with salvage
laryngectomy in the clinically N0 setting remain unclear.
The goals of this study are to determine the prevalence
of occult nodal disease, analyze nodal disease distribution
patterns, and identify predictors of occult nodal disease in a
salvage laryngectomy cohort. Histologically positive occult
nodes are identified in 17% of cN0 patients undergoing salvage
laryngectomy with neck dissection. Occult nodal disease varies in
frequency and distribution based on tumor subsite. Predictors of
high (>20%) occult nodal positivity include T4 tumors and
supraglottic subsite. In glottic LSCC, the most frequent sites of
occult nodal disease are the paratracheal nodal basins.